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For Healthcare Providers Frequently Asked Questions
Treat Covid - 19 from Home

PAXLOVID can be prescribed within 5 days of symptom onset and a positive COVID-19 test for adults who do not require supplemental oxygen and who are at increased risk for progressing to severe disease.1

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Click here to find more about how Malaysia is distributing PAXLOVID to patients.

Efficacy*

The efficacy of PAXLOVID was evaluated in 2246 adult COVID-19 patients at high risk for progression to severe disease in the EPIC-HR trial.2

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Drug Interaction Finder

Easily search for drug interactions by active substance name or keywords.

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Safety & Tolerability

During the EPIC-HR trial, comparable rates of adverse events were observed between the PAXLOVID and placebo groups.2

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 *These data present the results of the primary analysis for data collected up to December 2021.2
PAXLOVID is indicated for patients at high risk for
​​​progression to severe COVID-19
Any of the following risk factors can put a patient at risk for progressing to severe COVID-19:
  • Diabetes
  • Overweight (BMI >25)
  • Chronic lung disease (including asthma)
  • Chronic kidney disease
  • Current smoker
  • Immunosuppressive disease or treatment
  • Cardiovascular disease
  • Hypertension
  • Sickle cell disease
  • Neurodevelopmental disorders
  • Active cancer
  • Medically related technological dependence
  • 60 years of age and older, regardless of comorbidities 


A full list of risk factors from the CDC can be located at <local link>.

How PAXLOVID Works1,3

PAXLOVID contains nirmatrelvir, a protease inhibitor specifically designed by Pfizer to target the main protease (Mpro), also known as 3-chymotrypsin-like cysteine (3CL) protease enzyme, and to inhibit SARS-CoV-2 replication by preventing proteolysis from occurring. 

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Frequently Asked Questions​​​​​​​

Find answers to frequently asked questions on topics that include early treatment, dosing, and potential drug interactions.  

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References: 1.  Pfizer Malaysia PAXLOVID™ Prescribing Information, 29 September 2022  https://labeling.pfizer.com/ShowLabeling.aspx?id=17725. Assessed on 13th October 2022 2. Hammond J, Leister-Tebbe H, Gardner A, et al. Oral nirmatrelvir for high-risk, nonhospitalized adults with Covid-19. N Engl J Med. 2022;386(15):1397-1408. 3. Senger MR, Evangelista TCS, Dantas RF, et al. COVID-19: molecular targets, drug repurposing and new avenues for drug discovery. Mem Inst Oswaldo Cruz. 2020;115:e200254. 
PP-PAX-MYS-0108 13 October 2022

Adverse events should be reported. Reporting forms and information can be found at https://paxaes.pfizersafetyreporting.com

 

For medical questions related to PAXLOVID, you can visit  www.pfizer.com

PfizerPro AccountPfizerPro Account

To access further materials, resources and receive communication about medicines and vaccines promoted by Pfizer.

This site is intended only for healthcare professionals resident in to Malaysia. 

 

This website is brought to you by Pfizer Malaysia 

 

Copyright © 2022 Pfizer Limited. All rights reserved.

 

 

PP-PAX-MYS-0108 13 October 2022
For Malaysia Healthcare Professionals

These pages are not intended for patients or for members of the general public.

I confirm that I am a healthcare professional resident in Malaysia.

If you select 'No', you will be redirected to pfizerpro.com.my where you will be able to access reference information on PAXLOVID™ (PF-07321332; ritonavir)

I accept and agree to the Terms of Use*

TERMS OF USE - PAXLOVID

1. Use and content of this Web site. The information provided on this site is for general informational and educational purposes and has been approved by relevant regulatory authorities. 
Certain sections of this Web site are intended for Healthcare Professionals only and we ask you to not access these sections if you are not a Healthcare Professional. Specific appropriate sections have been developed and are accessible for the general public. Your access to and use of the information contained in the Web site is subject to this Terms of Use Agreement. By accessing and using this Web site, you accept, without limitation or qualification, this Terms of Use Agreement.
Neither Pfizer nor any party involved in creating, producing or delivering this Web site shall be liable for any damages, including without limitation, direct, incidental, consequential, indirect or punitive damages, arising out of access to, use of or inability to use this Web site, or any errors or omissions in the content thereof. This limitation includes damages to, or for any viruses that infect, your computer equipment.

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7. Copyrights. The entire contents of this Web site are subject to copyright protection. Copyright © 2020 Pfizer Inc. The contents of Pfizer Web sites may not be copied other than for non commercial individual reference with all copyright or other proprietary notices retained, and thereafter may not be recopied, reproduced or otherwise redistributed. Except as expressly provided in the website or above, you may not otherwise copy, display, download, distribute, modify, reproduce, republish or retransmit any information, text or documents contained in this Web site or any portion thereof in any electronic medium or in hard copy, or create any derivative work based on such images, text or documents, without the express written consent of Pfizer. Nothing contained herein shall be construed as conferring by implication, estoppel or otherwise any license or right under any patent or trademark of Pfizer, or any third party.

8. Void Where Prohibited. This Web site and its contents are intended to comply with the laws and regulations in Malaysia. Although the information on this Web site is accessible to users outside of Malaysia, the information contained on this website is intended for use only by residents of Malaysia. Other countries may have laws, regulatory requirements and medical practices that differ from those in Malaysia. Pfizer reserves the right to limit provision of its products or services to any person, geographic region or jurisdiction and/or to limit the quantities or any products or services we provide. Any offer for any product or service made on this Web site is void where prohibited.

9. Governing Laws. This Terms of Use Agreement and your use of the Web site shall be governed by the laws of Malaysia without regard to its conflicts of laws principles. Any legal action or proceeding related to this Web site shall be brought exclusively in a federal or state court of competent jurisdiction sitting in Malaysia.

10. Miscellaneous. If any provision of this Agreement is held to be unlawful, void or unenforceable, then such provision shall be severable without affecting the enforceability of all remaining provisions. Pfizer reserves the right to alter or delete materials from this Web site at any time at its discretion.

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